FDA approves Ionis ZANVASTRO, first treatment for Alexander disease

The FDA approved Ionis Pharmaceuticals' ZANVASTRO (zilganersen) on September 3, 2026, as the first disease-modifying treatment for Alexander disease. The RNA-targeted therapy reduces the protein that accumulates in astrocytes and is dosed every 12 weeks.

Detected & updated continuously · Source: Nebula

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Ionis Pharmaceuticals, Inc.Food and Drug Administration

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